C(=N)(NN)O gas chromatography (GC) (2) HPLC (2) Mass Shift +3 (1) Featured Industry. CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agency’s EPISuite, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:28306, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agency’s EPISuite, Compounds with the same molecular formula, Search Google for structures with same skeleton. Solubility: 100 g/l (15 c) Specific Gravity/Density:Not available. Semicarbazones and thiosemicarbazones can be prepared by treatment of a ketone or aldehyde with semicarbazide or thiosemicarbazide (Scheme 16).The reaction is general acid catalysed, and the yield of semicarbazone and the rate of reaction are dependent on the pH of the reaction medium < 32JA2881, 59JA475, 66BSB601 >. Some semicarbazones, such as nitrofurazone, and thiosemicarbazones are known to have anti-viral and anti-cancer activity, usually mediated through binding to copper or iron in cells. It can also be used to prepare corrosion inhibitors. CTK1H0495. Semicarbazide hydrochloride is a general reagent used to synthesize semicarbazones from aldehydes and ketones. Lopac-S-2201. Safety: IRRITANT Matrix Scientific 045167: Molecular Formula:CH5N3O.HCl Molecular Weight:111.53 Semicarbazide (SEM) carbamic acid hydrazide. Melting Point (°C) 101 - 200 (3) 201 - 300 (1) Application. It can be used to build a variety of heterocyclic compounds, some of which are potent antimicrobial and antiviral agents. Hydrazinecarboximidicacid (9CI) DTXSID7043823. CopyCopied, CSID:5008, http://www.chemspider.com/Chemical-Structure.5008.html (accessed 06:09, Nov 29, 2020) BDBM50108606. Many semicarbazones are crystalline solids, useful for the identification of the parent aldehydes/ketones by melting point analysis.[1]. Packaging 100, 500 g … Compounds Containing a N-CO-N-N or More Complex Group, https://en.wikipedia.org/w/index.php?title=Semicarbazone&oldid=954547442, Creative Commons Attribution-ShareAlike License, This page was last edited on 3 May 2020, at 00:35. CARBAMOHYDRAZONIC ACID. This is an example of imine formation resulting from the reaction of a primary amine with a carbonyl group. Advanced Search | Structure Search. CTK4I8064. Some semicarbazones, such as nitrofurazone, and thiosemicarbazones are known to have anti-viral and anti-cancer activity, usually mediated through binding to copper or iron in cells. The formation of semicarbazones from ketones can be catalysed by the … Semicarbazide is frequently reacted with aldehydes and ketones to produce semicarbazones via a condensation reaction. BBL012207. Freezing/Melting Point:175.00 - 177.00 deg C Decomposition Temperature:Not available. Experimental Melting Point: 231 °C Jean-Claude Bradley Open Melting Point Dataset 9358: 213.5 °C Biosynth J-501846: 231 °C MolMall 20474: 213.5-217.5 °C Sigma-Aldrich ALDRICH-568449: Experimental LogP: 0.744 LabNetwork LN00240254: Miscellaneous. 4-03-00-00177 (Beilstein Handbook Reference) [N]NC(N)=O. Many semicarbazones are crystalline solids, useful for the identification of the parent aldehydes/ketones by melting point analysis. Experimental Melting Point: 96 °C Jean-Claude Bradley Open Melting Point Dataset 21559: Experimental Boiling Point: 186.3 °C Chemenu CM186660: Experimental LogP:-2.166 LabNetwork LN01075682: Miscellaneous. Boiling Point: Not available. semicarbazide group. Clinical (1) ... Semicarbazide hydrochloride. They are classified as imine derivatives because they are formed from the reaction of an aldehyde or ketone with the terminal -NH2 group of semicarbazide, which behaves very similarly to primary amines. Semicarbazide hydrochloride. CTK1H0745. A monocarboxylic acid amide that is urea where one of the amino groups has been replaced with hydrazine. For example, the semicarbazone of acetone would have the structure (CH3)2C=NNHC(=O)NH2. The reaction is useful because semicarbazones, like oximes and 2,4-DNPs, typically have high melting points and crystallize, facilitating purification or identification of reaction products. CopyCopied, InChI=1S/CH5N3O/c2-1(5)4-3/h3H2,(H3,2,4,5) Lopac0_001096. Semicarbazide, 6 wt% on Silica gel. ZINC8035043. In organic chemistry, a semicarbazone is a derivative of imines formed by a condensation reaction between a ketone or aldehyde and semicarbazide. A thiosemicarbazone is an analog of a semicarbazone which contains a sulfur atom in place of the oxygen atom. CopyCopied, DUIOPKIIICUYRZ-UHFFFAOYSA-N Chemical Class: Is urea where one of the oxygen atom, some of which potent. Molecular Weight:111.53 melting Point analysis. [ 1 ] Weight:111.53 melting Point analysis. 1. Have the structure ( CH3 ) 2C=NNHC ( =O ) NH2 101 - 200 ( 3 ) 201 300! Crystalline solids, useful for the identification of the parent aldehydes/ketones by melting Point ( °C ) 101 200! Some of which are potent antimicrobial and antiviral agents imines formed by a reaction. Synthesize semicarbazones from aldehydes and ketones to produce semicarbazones via a condensation reaction between ketone. 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