The facility is normally open Monday–Friday, 9 a.m.–6 p.m. We are closed for all official university holidays. Miller MS, Maheshwari S, Shi W, Gao Y, Chu N, Soares AS, Cole PA, Amzel LM, Fuchs MR, Jakoncic J, Gabelli SB. Users will need to contact the facility manager in advance to set up a training session. Wood Basic Science Building, Room 512. Fax: 410-516-8420 The Johns Hopkins Mass Spectrometry and Proteomic Facility. We provide specialty … The most up-to-date information on instrument availability can be found on our Instrument Status and News page. Find a doctor at The Johns Hopkins Hospital, Johns Hopkins Bayview Medical Center or Johns Hopkins Community Physicians. 725 N. Wolfe Street. Users are required to treat all instruments with care and respect and to maintain their competence in order to retain usage privileges. The Johns Hopkins Germ-free Core is ~1500 square feet with 3 animal rooms, dedicated autoclave and two work rooms. The facility’s primary role is to support chemical research conducted within the department, but it is also available for use by researchers from other JHU departments and divisions, along with those from external institutions and commercial organizations. Learn about our expanded patient care options and visitor guidelines. We primarily work with blood or urine specimens, but we have the capability to work with alternative samples such as tissue, DBS, or sputum. Cell. 74. Our clinical mass spectrometry laboratory is equipped with a variety of chromatographic equipment and mass analyzers, including multiple high-resolution accurate mass instruments. Rm. The Johns Hopkins AIMS Core provides comprehensive service in MALDI tissue imaging to investigators at Johns Hopkins and outside. Yoder JB, Ben-Johny M, Farinelli F, Srinivasan L, Shoemaker SR, Tomaselli GF, Gabelli SB, Amzel LM. Effects of copper occupancy on the conformational landscape of peptidylglycine α-hydroxylating monooxygenase. During his time here, he has overseen the overhaul and upgrading of the facility’s instrumentation and developed and updated operational procedures for the MSF. All users (including those who wish to submit samples for analysis on “full-service” instruments) will need to establish an account with the department for instrument access and billing purposes. To establish an account, please download and complete the PDF Document: Chemistry Core Facility Access Form and return it to the facility manager. of Biophysics and Biophysical Chemistry. The Mass Spectrometry Core couples multi-dimensional separations by column chromatography or gel electrophoresis to mass spectrometry analysis. 2019 Jan 30;24(3). Epub 2018 Aug 2. Johns Hopkins University. 725 N. Wolfe Street. Our clinical mass spectrometry laboratory is equipped with a variety of chromatographic equipment and mass analyzers, including multiple high-resolution accurate mass instruments. Email: RCole@jhmi.edu. … Phone: 410-614-6968. The facility is managed by Dr. Phil Mortimer and is located in the basement of Remsen Hall on the University’s Homewood Campus. Sandra B. Gabelli ... Mass Spectrometry Core … We look forward to working with you in the future. The Johns Hopkins Applied Imaging Mass Spectrometry (AIMS) Core/Service Center provides rapid matrix-assisted laser desorption/ionization (MALDI) imaging at high spatial resolution, which includes sample preparation, on-tissue digests and derivatizations, and data analysis. Phone: 410-614-6968. Training is normally conducted in small groups of less than three people, due to limited space in the instrument labs. We welcome enquiries into the use of these instruments. Users wishing to utilize one of our “self-service” instruments (GC-MS, LC-MS, ESI-MS or Maldi-ToF) will need to participate in a training session on the relevant instrument and demonstrate competence before being issued operating privileges and access credentials. © 2020 Johns Hopkins University, Zanvyl Krieger School of Arts & SciencesThe Chemistry Department Mass Spectrometry FacilityRemsen Hall B133400 N. Charles St., Baltimore, MD 21218Tel: 410-516-5552 | Fax: 410-516-8420mass.spec@jhu.edu, The Chemistry Department Mass Spectrometry Facility, Sample Preparation and Submission Guidelines. Communications Biology. We belong to the Cellular and Molecular Medicine Graduate program (CMM). pii: E496. Nat Commun. Johns Hopkins University We are providing in-person care and telemedicine appointments. A separate form will be required for each user who wishes to use our facilities. Tel: 410-516-5552. B13, Remsen Hall, Homewood Campus. We continue to monitor COVID-19 cases in our area and providers will notify you if there are scheduling changes. Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II. We provide specialty clinical testing for therapeutic drug monitoring and clinical toxicology, with both quantitative and qualitative LC-MS methods. Molecules. doi: 10.3390/molecules24030496.. See the new protopedia pages of some of our fav macromolecules https://proteopedia.org/wiki/index.php/NudT16 https://proteopedia.org/wiki/index.php/FPPS https://proteopedia.org/wiki/index.php/WWP2...... Read More, Katie Wright won the fellow research day poster session first place for basic Research (May 2020)...... Read More, Tihitina Aytenfisu won the PURA Award to carry out research in the lab....... Read More, Hannah Campbell joins the lab as part of the Sr. Alma Nicholas Science Year experience – Notre Dame of Maryland...... Read More, See the new protopedia pages of some of our favorite molecules, Katie Wright won first place in poster session for basic Research, Johns Hopkins Fundamentals – A closer look at basic biomedical research, We are part of the Structural Enzymology and Thermodynamics Group at the Dept. MALDI imaging combines mass spectrometric analyses of biomolecules with simultaneous histological evaluation to analyze intact proteins, peptides and tryptic peptides (on-tissue tryptic digest), N-glycans (on-tissue PNGase digest), lipids, metabolites and drug molecules in a spatially resolved manner.

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